The Bavarians stormed to a five-goal first-leg advantage three weeks ago, with Robert Lewandowski and Thomas Müller bagging braces either side of a Kingsley Coman strike at the Allianz Arena, and will surely fancy their chances of making the last eight for the seventh year running.
Having sat out of the 6-0 drubbing of Hamburg with a calf complaint on Saturday, James should come back into the side. Indeed, Heynckes may opt to rotate from back to front, with a trip to RB Leipzig coming as soon as next Sunday. Midfielder Corentin Tolisso is a major doubt, however, after suffering severe bruising to his shin against HSV and will be assessed further in the run-up to the trip to Istanbul.
Besiktas are without the suspended defender Domagoj Vida after his red card at the Allianz, but they will have an in-form Ricardo Quaresma to call upon. The Portuguese winger has provided four assists in the competition so far and scored against Bayern in a knockout tie for Porto in 2014/15.
Last season’s Turkish SuperLig winners currently sit second in the domestic standings, having won all three of their top-flight assignments since losing so comprehensively in Munich. A much-changed side won 1-0 at relegation-threatened Genclerbirligi on Saturday.
Besiktas: Fabri – Caner, Pepe, Gökhan Adriano – Medel, Hutchinson (c) – Quaresma, Talisca, Babel – Love
Absentees: Vida (suspended)
Coach: Senol Gunes
Bayern: Ulreich – Rafinha, Boateng, Süle, Alaba – Rudy, Martinez – Müller (c), James, Ribery – Lewandowski
Absentees: Neuer (foot), Coman (ankle)
Coach: Jupp Heynckes